Top 10 Infinitus Alternatives

Introduction

Insurance-heavy specialties run on different economics than a typical outpatient practice. More than one in ten U.S. adults, roughly 37 million people, live with chronic kidney disease, according to the Centers for Disease Control and Prevention, and many of them cycle through a nephrology group's eligibility and authorization workflow multiple times a year. A nephrology group managing patients on dialysis works through Medicare's ESRD entitlement rules, secondary commercial coverage, and prior authorization on top of it, often for the same patient in the same month. A urology practice submitting authorization for an in-office procedure or an oncology-adjacent treatment faces payer rules that change without much notice and denial reasons that take days to track down. When a point solution like Infinitus only automates one slice of that work, typically the payer phone call itself, the CFO or VP of Operations is left stitching together eligibility checks, authorization submissions, and follow-up into a workflow with more manual handoffs than the leadership team would like.

That gap is why organizations start evaluating Infinitus alternatives in the first place. Some want broader workflow coverage that includes eligibility and authorization together rather than as separate purchases. Some want a platform that writes results directly into the EHR instead of leaving staff to transcribe an outcome from a call log. And some are simply trying to reduce the number of vendors a lean revenue cycle team has to manage while still getting faster, more reliable answers from payers. For a closer look at how these pieces fit together operationally, see our guide to coordinating scheduling, billing, and follow-ups in a single connected workflow.

This guide covers why organizations look for Infinitus alternatives, how we evaluated each platform, a quick-glance comparison, and 10 platforms worth a look in 2027, starting with Confido Health.

Why Organizations Look for Alternatives to Infinitus

Most organizations do not leave a payer-calling tool because it fails at what it does. They leave, or look elsewhere, because the scope of the problem has grown past what a single-purpose tool was built to solve, and because the regulatory and payer environment around prior authorization keeps getting more demanding. A 2022 Office of Inspector General report found that 13 percent of prior authorization denials it reviewed actually met Medicare coverage rules and should have been approved, and 18 percent of payment denials met Medicare and billing rules as well, underscoring how much inconsistency still exists in how payers handle these requests. Federal rules are tightening the other side of the equation too. The CMS Interoperability and Prior Authorization Final Rule requires most impacted payers to decide expedited requests within 72 hours and standard requests within 7 calendar days starting in 2026, with electronic prior authorization API requirements phasing in through January 2027, a timeline that assumes providers can submit and track authorizations electronically rather than by phone or fax.

Scope. A platform built primarily around automating outbound payer calls covers one piece of the insurance workflow, leaving eligibility capture, authorization submission, and denial follow-up as separate manual steps or separate vendor purchases.

EHR write-back. Some payer-calling tools return an answer to a dashboard or a log rather than writing the result directly into the patient chart, which means staff still have to find the information and enter it themselves.

Patient Process: Insurance verification does not happen in isolation. It connects to scheduling, patient outreach for coverage gaps, and billing, and a tool that only handles the payer call misses the chance to close that loop automatically.

How We Evaluated Infinitus Alternatives

We evaluated each of these Infinitus alternatives the way a CFO or VP of Operations at an insurance-heavy specialty group would, weighing the factors that decide whether a platform actually reduces manual work rather than shifting it.

Workflow breadth. Whether the platform handles eligibility verification and prior authorization together, or only one piece of the insurance workflow.

EHR and PMS write-back. Whether verified eligibility data and authorization outcomes flow automatically into the patient chart, rather than requiring staff to transcribe results.

Payer coverage and connections. How many payers and how much of the U.S. covered-lives population the platform can reach directly.

Accuracy and clinical documentation handling. Whether the platform can extract and submit the clinical documentation payers require, rather than only checking status.

Specialty and case complexity fit. Whether the platform is built to handle the authorization and eligibility complexity specific to insurance-heavy specialties, not just high-volume, low-complexity primary care visits.

Deployment speed and staff burden. How long implementation takes and how much staff time it actually removes rather than redistributes.

Security and compliance. HIPAA compliance and Business Associate Agreements.

For a broader look at how these platforms fit into the wider patient access and revenue cycle landscape, see our roundup of top AI healthcare companies.

Comparison Table: Top Infinitus Alternatives at a Glance

Top 10 Infinitus Alternatives

Here are 10 Infinitus alternatives worth evaluating, starting with our pick for insurance-heavy specialty groups managing eligibility and authorization at scale. Each of these Infinitus alternatives approaches the payer relationship differently, so the right fit depends on how much of the insurance workflow your organization wants a single platform to own.

1. Confido Health

Overview

Confido Health is the AI system of action for healthcare operations, built to carry insurance work from the eligibility check to the authorization decision without a manual handoff in between. Its AI agents work inside the EHR, PMS, and phone systems an organization already runs. They verify coverage before the visit, check whether a service needs authorization, submit requests through payer and IPA portals, follow up while a request is pending, and contact payers to confirm denial reasons and resubmit with the right documentation. The same agents work across phone, fax, text, and email, so a faxed order or a patient call moves from request to resolution instead of waiting in a queue, and staff step in only when a case needs clinical judgment. Every finished task writes back to the EHR or PMS, and the same platform extends to scheduling, referrals, and payments across front, mid, and back office work. Confido Health supports 50+ EHR, PMS, and phone systems, goes live within 30 days from kickoff, and is SOC 2 Type II and HIPAA compliant.  

Workflow Offerings

• Pre-visit eligibility checks through clearinghouse integration, with real-time copay and deductible retrieval written directly to the patient chart
• Prior authorization requirement checks, submission through payer and IPA portals, and status inquiries handled end-to-end without staff opening a payer portal
• Denial reason clarification and structured resubmission, including HMO and IPA edge case handling
• Authorization renewal reminders and payer outreach for missing or incomplete information, closing gaps before they delay a scheduled procedure
• Outreach to patients with incomplete or expired coverage on file, resolving eligibility gaps before the visit rather than at check-in

Key Integrations

Confido Health offers real-time, two-way integrations across 50+ EHR, PMS, and phone systems, and it adds new integrations every month. The list includes Epic, athenahealth, eClinicalWorks, NextGen, Allscripts, DrChrono, Practice Fusion, Veradigm, Tebra, and Cerner, along with telephony systems including RingCentral, 3CX, and Mango Voice.

Strengths

From our experience working with insurance-heavy specialty groups, putting eligibility and prior authorization inside one system of action shortens the distance between a scheduled visit and a clean claim. Confido Health reports:

• Eligibility in minutes, not hours of desk time: Front desk time on manual eligibility checks drops from 10 to 15 minutes per patient to near zero, with results written back to the patient chart.
• Authorization decisions in hours, not days: Prior authorization turnaround falls from 5 to 14 days to 2 to 4 hours with electronic submission.
• Faster end-to-end authorization: Prior authorization processing runs 75 percent faster than manual workflows.
• Fewer denials at the source: Complete, automated submissions lead to 30 percent fewer initial denials.
• Fast deployment: Confido Health goes live 4 to 6 weeks from kickoff, and measurable impact is typically visible within 60 to 90 days.
• Security and compliance: Confido Health is SOC 2 Type II and HIPAA compliant.

Considerations

Confido Health's prior authorization and eligibility workflows cover the payer types and case complexity most insurance-heavy specialty groups encounter, but organizations working almost exclusively with a small number of regional payers with highly nonstandard portals should confirm coverage for those specific payer connections during evaluation.

Best For

Insurance-heavy specialty groups, including nephrology and urology practices, wanting eligibility verification, prior authorization, and payer outreach handled inside one AI-driven operations platform rather than a single-purpose payer-calling tool. Among Infinitus alternatives evaluated for this guide, it is the only one built around all three at once.

2. Cohere Health

Overview

Among Infinitus alternatives built specifically for payer-side utilization management, Cohere Health provides clinical-grade prior authorization decision support built primarily for the payer side of the relationship, with a provider-facing portal that submits requests directly into health plan utilization management systems. The platform automatically sources clinical information from attachments to reduce manual data entry and routes complex cases to physician and nurse review teams when automated decisions are not possible.

Strengths

Cohere reports 94 percent provider adoption where deployed, with 85 percent of properly documented requests achieving real-time approval and integration with major EHR and practice management systems, including Epic and athenahealth.

Considerations

Cohere Health's tools are built around the specific health plans that have adopted its utilization management platform, so its usefulness for a given practice depends heavily on whether the relevant payers participate.

Best For

Providers wanting clinical-grade prior authorization decision support with direct integration into participating health plans' utilization management systems.

3. Availity

Overview

Availity is one of the larger Infinitus alternatives by sheer network reach, operating one of the largest health information networks in the country, connecting providers to payers for eligibility, claims, and authorization transactions. Its End-to-End Authorizations product supports configurable routing by provider type and specialty, multiple submission channels including API and direct portal, and AI-assisted review intended to automate a large share of routine utilization management work.

Strengths

Availity's scale, reportedly facilitating billions of transactions annually across its network, is its clearest advantage for organizations that already touch the platform through payer connections.

Considerations

Because Availity's authorization tooling is oriented toward the payer side of the relationship, provider organizations should confirm how much of the automation benefit reaches their own staff workflow rather than the health plan's internal review process.

Best For

Organizations wanting authorization and eligibility connectivity across the largest payer network in the country.

4. Infinx

Overview

Infinx positions itself among Infinitus alternatives that pair automation with human specialists, combining an AI-driven authorization determination engine with specialist follow-up support, aiming to identify whether a prior authorization is required and, if so, submit and track it through resolution. The company reports over 98 percent accuracy on authorization determinations, connections to more than 1,400 national and regional payers, and average turnaround of 24 to 48 hours for standard procedures.

Strengths

The blended AI-plus-specialist-team model is Infinx's differentiator, useful for organizations that want automation backed by a human team handling exceptions.

Considerations

Organizations evaluating Infinx should clarify how much of the workflow is software-driven versus handled by Infinx's own specialist staff, since that mix affects both cost and turnaround expectations.

Best For

Practices wanting prior authorization determination and submission combined with dedicated specialist follow-up support.

5. Myndshft

Overview

Myndshft is one of the Infinitus alternatives built primarily around payer rules coverage, automating the prior authorization workflow from the point an order is placed through submission, verification, and tracking, using a payer rules engine that the company says covers 94 percent of U.S. covered lives. Real-time member data access and generative AI-driven routing are built to reduce the manual research staff would otherwise do to identify the correct submission path for each payer.

Strengths

Myndshft reports a 93 percent improvement in benefits turnaround time and up to a 90 percent reduction in manual authorization tasks among its clients.

Considerations

Myndshft's core strength is payer rules coverage rather than a broader connected patient access workflow, so organizations should evaluate how authorization outcomes feed back into scheduling and billing on their end.

Best For

Organizations wanting a payer rules engine that automates authorization routing across most U.S. covered lives.

6. AKASA

Overview

AKASA is a narrower entry among Infinitus alternatives, with its Authorization Advisor using generative AI to check authorization status directly from payer portals, interpret the often inconsistent language payers use in their responses, and log the result for staff review. It is built to sit alongside an existing revenue cycle team rather than replace the submission and clinical documentation steps.

Strengths

A case study cited by AKASA reports a 22 percent reduction in authorization work queue volume after implementation.

Considerations

AKASA's authorization tooling focuses specifically on status checking rather than full submission or eligibility verification, so organizations typically pair it with other tools to cover the rest of the workflow.

Best For

Health systems wanting AI-driven authorization status checks layered onto an existing revenue cycle team.

7. Waystar

Overview

Waystar is one of the Infinitus alternatives that folds authorization into a much larger revenue cycle suite, bundling eligibility verification and prior authorization tools into its broader revenue cycle platform, aiming to give organizations a single system for the financial and administrative work around a patient visit rather than separate point tools. Its scale in claims processing gives it a large base of payer connections to draw on for both eligibility and authorization checks.

Strengths

Waystar's breadth across the revenue cycle, from eligibility through claims and denial follow-up, is its main advantage for organizations wanting fewer vendor relationships.

Considerations

Because Waystar's authorization and eligibility tools are part of a much larger revenue cycle suite, organizations evaluating it specifically as an Infinitus alternative should confirm pricing and functionality when deployed narrowly rather than as the full platform.

Best For

Organizations wanting authorization and eligibility bundled into a broader revenue cycle platform.

8. Experian Health

Overview

Experian Health rounds out the Infinitus alternatives anchored in registration accuracy, tying eligibility verification closely to accurate patient registration, using automated data capture and insurance card scanning to reduce the manual entry errors that often cause downstream denials. Its authorization tools are built to work alongside these registration and eligibility products rather than as a standalone offering.

Strengths

Experian Health cites internal research finding a majority of patients prefer a digital registration experience over paper-based intake, framing its accuracy-first approach around reducing errors at the source.

Considerations

Experian Health's authorization functionality is closely tied to its broader registration suite, so organizations should confirm how it performs when evaluated as a standalone eligibility and authorization tool.

Best For

Groups wanting eligibility verification tied closely to registration accuracy and cost estimation.

9. Notable Health

Overview

Notable Health is one of the Infinitus alternatives that bundles authorization with intake and scheduling, combining prior authorization automation with intake, scheduling, and referral management inside a single patient access platform, aiming to reduce the number of separate systems a health system needs for administrative work. Its AI-driven workflows handle fax and referral processing alongside authorization tasks.

Strengths

Notable reports substantial reductions in fax processing turnaround time and meaningful call deflection for portal-related support issues.

Considerations

Notable's authorization capabilities sit inside a broader access automation suite, so organizations focused narrowly on insurance verification and prior authorization should confirm how the platform is scoped and priced outside the full bundle.

Best For

Health systems wanting prior authorization automation bundled with intake and scheduling workflows.

10. Optum (Change Healthcare)

Overview

Optum is among the largest-scale Infinitus alternatives, with its Change Healthcare platform offering eligibility verification and prior authorization tools built on one of the largest clearinghouse networks in the country, giving it broad payer reach for organizations already connected to its claims infrastructure. Its scale makes it a familiar option for large health systems standardized on Optum's broader revenue cycle stack.

Strengths

Optum's clearinghouse scale is its clearest advantage, particularly for organizations that already route claims and eligibility transactions through its network.

Considerations

Because Optum's authorization tools are part of a much larger enterprise revenue cycle suite, smaller insurance-heavy specialty groups should confirm implementation timelines and cost relative to more focused alternatives.

Best For

Enterprise health systems already standardized on Optum's clearinghouse and revenue cycle stack.

What Nephrology and Urology Practices Should Weigh Before Switching

Insurance-heavy specialties carry authorization and eligibility complexity that a general-purpose tool is not always tuned for, so the decision to move off Infinitus and evaluate other Infinitus alternatives deserves a closer look at case mix before committing.

Nephrology groups managing dialysis patients work through Medicare's End-Stage Renal Disease entitlement rules alongside commercial secondary coverage, often for the same patient across the same month, which means eligibility and authorization checks need to run more frequently and more accurately than in a typical outpatient setting. Urology practices submitting authorization for in-office procedures or oncology-adjacent treatments face payer documentation requirements that shift with little notice, and a missed or incomplete submission can delay a time-sensitive procedure by days. In both cases, the cost of a slow or incomplete authorization workflow is measured in delayed care, not just administrative time.

Before switching platforms, map out which authorization types your organization submits most often, confirm how many of your top payers each candidate among these Infinitus alternatives actually reaches, and ask each vendor to show a real authorization submission for a case similar to what your specialty handles rather than a generic demo. A platform that performs well on eligibility checks but struggles with your specific authorization mix has not solved the problem driving the search for Infinitus alternatives in the first place.

Why CFOs and VPs of Operations Choose Confido Health Over Point Solutions

Compared with narrower Infinitus alternatives built around a single payer workflow, Confido Health is designed to own the full eligibility and authorization relationship for insurance-heavy specialty groups for CFOs and VPs of Operations evaluating a replacement.

Eligibility and authorization handled inside one conversation

Confido Health's AI agents check eligibility, submit prior authorizations, and follow up with payers as part of the same connected system that also manages scheduling and patient outreach, rather than requiring a separate tool for each step. For a closer look at how this plays out across a growing organization, see our guide to multi-location patient access.

Faster turnaround backed by real numbers

Confido Health reports prior authorization turnaround falling from 5 to 14 days down to 2 to 4 hours with electronic submission, and 30 percent fewer initial denials from complete, automated submissions- numbers CFOs can hold vendors accountable to during evaluation.

Built for insurance-heavy specialty complexity

Confido Health's authorization workflows handle HMO and IPA edge cases, denial reason clarification, and structured resubmission- the kind of complexity that nephrology, urology, and other insurance-heavy specialty groups deal with routinely rather than occasionally.

Fast deployment without adding headcount

Typical implementation takes under 30 days, with measurable operational improvements often visible within 60 to 90 days. You can estimate your own numbers with our ROI calculator tool.

Final Thoughts

Among the Infinitus alternatives covered here, the right one depends on how much of the insurance workflow you want one platform to own. Cohere Health, Availity, and Optum fit organizations already anchored to a specific health plan or clearinghouse network. Infinx and Myndshft lead on payer rules coverage and determination accuracy. AKASA fits organizations wanting to layer automation onto an existing team rather than replace the workflow. Waystar, Experian Health, and Notable Health each bundle authorization into a broader platform built around a different core strength. Confido Health is built for insurance-heavy specialty groups that want eligibility verification, prior authorization, and payer outreach working together inside one AI-driven operations platform, not stitched together from separate tools.

Before you choose among these Infinitus alternatives, map your authorization mix, confirm payer coverage for the plans your organization actually bills, and ask each vendor to show their platform handling a case similar to what your specialty submits every week, not a generic example.

Want to see how Confido Health handles insurance verification and prior authorization for a practice like yours? Book a demo to get started, or explore our specialty webinars for a closer look at workflows like these.

Frequently Asked Questions

What is Infinitus?

Infinitus is a healthcare AI platform known for automating payer-facing phone calls, including benefits verification and prior authorization follow-up calls, primarily for payers, providers, and life sciences companies.

Why are organizations looking for Infinitus alternatives?

Organizations evaluating Infinitus alternatives often want broader workflow coverage that includes eligibility verification and prior authorization together, direct EHR write-back, and a connection to the rest of patient access rather than a tool focused mainly on the payer call itself. For teams with those priorities, Confido Health is one option worth a look, since its AI agents handle eligibility verification and prior authorization inside the EHR, PMS, and phone systems a practice already runs, and write each finished task back to the record.

Is Confido Health a good Infinitus alternative for nephrology or urology practices?

Confido Health handles eligibility verification and prior authorization together, including denial reason clarification and structured resubmission, which fits the recurring authorization and coverage complexity that nephrology and urology practices deal with regularly.

Does Confido Health integrate with the EHR we already use for eligibility checks?

Confido Health offers real-time, two-way integrations across more than 50+ EHR, PMS, and phone systems, including Epic, athenahealth, eClinicalWorks, and NextGen, with new integrations added monthly.

How is Confido Health different from Infinitus?

Confido Health handles eligibility verification, prior authorization, scheduling, and patient outreach inside one connected platform with direct EHR write-back, while Infinitus is primarily known for automating payer phone calls as a more narrowly scoped tool. This broader scope is a common thread among the strongest Infinitus alternatives on this list.

What should a CFO evaluate before switching from Infinitus to another platform?

Confirm payer coverage for the specific plans your organization bills most often, ask for a live demonstration using a case similar to your specialty's authorization mix, and clarify how much of the outcome writes back automatically versus requiring manual entry.

How fast can we deploy Confido Health as an Infinitus alternative?

Typical implementation takes under 30 days, with measurable operational improvements in prior authorization turnaround and eligibility checks often visible within 60 to 90 days.

Is Confido Health HIPAA compliant?

Confido Health is HIPAA compliant and SOC 2 Type II certified. Confirm Business Associate Agreement terms, encryption standards, and audit logging directly with any vendor during evaluation.

What are the best Infinitus alternatives for insurance-heavy specialties?

Among the Infinitus alternatives covered in this guide, Confido Health, Cohere Health, and Infinx are the most relevant starting points for insurance-heavy specialties like nephrology and urology, since each handles prior authorization determination and submission rather than only status checking. Confido Health additionally covers eligibility verification, scheduling, and patient outreach inside the same platform.