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- This guide is for CFOs and VPs of Revenue Cycle at multi-location groups with 10 or more providers, where revenue leaks through eligibility gaps, stalled authorizations, unworked denials, and patient balances nobody calls about.
- Revenue cycle management software covers 3 kinds of work: claims and coding engines, payer connectivity, and the payer and patient work that decides whether a claim goes out clean and gets paid.
- The 10 platforms below are ranked for multi-location groups, starting with Confido Health, which runs the payer and patient work across the revenue cycle inside the billing system a group already uses.
- For where AI fits across the cycle, see our breakdown of AI in revenue cycle management and our guide to insurance verification and prior authorization
Introduction
It is the last Tuesday of the quarter, and the VP of Revenue Cycle at a 35-location specialty group is reviewing the aging report before the board meeting. Denial write-offs are up again. About a third trace back to eligibility and authorization problems that should have been caught before the visit. Another slice is patient balances that aged past 90 days because nobody had time to call.
The billing system is doing what it was built to do. It submits claims and posts payments. What it does not do is pick up the phone: to the payer about a pending authorization, to the payer about a denial, or to the patient about a balance. That work still sits with staff, and at group scale it outruns them.
This guide covers what is driving RCM decisions for multi-location groups, how we evaluated each platform, a comparison of 10 platforms, and how to choose.
Why Multi-Location Groups Are Rethinking Revenue Cycle Software
Denials keep rising
In a 2024 MGMA Stat poll, 60% of medical group leaders reported higher claim denial rates than the year before, and only 11% reported a decrease.
Much of the loss starts before the claim
Many denials trace to eligibility and authorization problems that a conversation before the visit would have caught. Claims engines can flag a missing authorization number, but they cannot make the call that would have prevented it.
Patient balances need conversations
As patient responsibility grows, more revenue depends on reaching patients with clear answers about what they owe and how to pay. Statements alone leave much of it uncollected.
Vendor concentration is now a risk factor
The 2024 Change Healthcare cyberattack showed how much of the industry runs through shared claims infrastructure. In an AHA survey, 94% of hospitals reported financial impact. CFOs now weigh resilience alongside capability.
Groups run mixed systems
Groups that grow through acquisition often run several EHRs and billing systems. The revenue cycle has to work across all of them.
How We Evaluated These Platforms
- Coverage of the cycle. Which parts of eligibility, authorization, claims, denials, and patient payments the platform handles.
- Payer and patient work. Whether the platform makes the payer calls and patient billing conversations, or leaves them on staff.
- Denial prevention and recovery. Whether it stops denials before submission, works them after, or both.
- Integration. Whether it reads and writes to the EHR, PMS, and billing systems the group runs.
- Fit for group scale. Whether it is built for multi-location groups or sized for hospital systems.
- Delivery model. Software the group runs, or an outsourced service.
Comparison Table: Top RCM Platforms at a Glance
Top 10 Revenue Cycle Management Software Platforms
1. Confido Health
Overview
Confido Health is the AI system of action for healthcare operations. In the revenue cycle, its AI Teammates run the payer and patient work that decides whether a claim goes out clean and gets paid, inside the EHR, PMS, billing, and phone systems a group already runs. Before the visit, they verify eligibility and benefits, check authorization requirements, submit authorizations, and follow up with payers until a decision comes back. After a denial, they classify it by reason, call the payer to confirm what is missing, correct and resubmit the claim, and track the appeal to resolution. On the patient side, they explain balances, enroll payment plans, send payment reminders, and run collections calls. Every update writes back to the EHR or PMS. Confido Health is live across 500+ providers and 1,000+ locations.
Revenue Cycle Capabilities
- Eligibility, benefits, and network verification at scheduling, written to the chart
- Authorization requirement checks, portal submission, and payer follow-up
- Denial classification, payer calls, correction, resubmission, and appeal tracking
- Denial reasons fed back into front-end checks, so the same denial does not repeat
- Patient balance explanations, payment plan enrollment, and copay and deductible collection
- Payment reminders, collections calls, and failed payment retries
- Payer and patient conversations in 20+ languages
- Reporting by location, payer, and service line
Customer Results
- A 70-location ophthalmology group handled 58,000+ financial services calls in 11 months with Confido Health. AI Teammates now handle more than 97% of outbound financial calls, and monthly collections grew to more than 3 times prior levels.
- Dallas Renal Group, a 51-location nephrology network, recovers $30,000+ in revenue each month from missed patients.
Key Integrations
Two-way integrations across 40+ EHR, PMS, and phone systems, including Epic, athenahealth, eClinicalWorks, NextGen, ModMed, and Veradigm, plus phone systems such as RingCentral, 3CX, and Mango Voice.
Strengths
Confido Health does the work most RCM software leaves on staff: the payer call about a pending authorization, the payer call about a denial, and the patient call about a balance. It runs inside the billing system a group already uses, so there is no rip-and-replace, and one standard runs at every location. Confido Health is HIPAA compliant and SOC 2 Type II certified.
Getting Started
Most groups start with the revenue cycle step losing the most money, often patient collections or eligibility and authorization, then add denial follow-up and more locations on the same platform.
Best For
Multi-location groups with 10+ providers that want payer and patient work across the revenue cycle handled end to end, inside their existing billing system.
2. Waystar
Overview
Waystar is an RCM platform focused on claims, payments, and denial and payment integrity.
Capabilities
- Claims clearinghouse and eligibility verification
- AltitudeAI for denials and appeals
- Recoupment Manager for payment take-backs
- Payment integrity analytics
Key Integrations
Connects with major EHR and practice management systems.
Strengths
Waystar reports a health system surfacing $32 million in previously undetected recoupments with Recoupment Manager.
Considerations
Waystar works the claim and the remittance. Payer calls and patient billing conversations still fall on staff.
Best For
Groups and health systems wanting claims, denials, and payment integrity.
3. Experian Health
Overview
Experian Health focuses on the front end of the revenue cycle through its eCare NEXT platform and AI Advantage claims technology.
Capabilities
- Eligibility and benefits verification
- Prior authorization status checks
- Denial prediction before submission
- Payer requirements knowledgebase
Key Integrations
Integrates across the revenue cycle from eligibility through patient payments.
Strengths
Strong front-end tooling for eligibility and authorization.
Considerations
When a verification or authorization needs a payer conversation, staff still make the call.
Best For
Organizations wanting front-end eligibility and authorization tools.
4. Availity
Overview
Availity operates a large health information network handling clinical, administrative, and financial transactions across the revenue cycle.
Capabilities
- Financial clearance and prior authorization submission
- Claims submission with predictive editing
- Remittance, denial prevention, and appeals
- Patient statements and payments
Key Integrations
Direct connectivity to a nationwide payer network.
Strengths
Broad payer reach for claims and eligibility.
Considerations
Availity is a connectivity layer, so payer follow-up and patient conversations still need a team or another tool.
Best For
Organizations wanting broad payer connectivity and claims processing.
5. FinThrive
Overview
FinThrive is an RCM platform built around FinThrive Fusion, a data layer that connects EHRs, billing systems, and payer portals.
Capabilities
- Patient access, eligibility, and authorization
- Charge management and compliance
- Claims, contracts, denial prevention, and AR
- Predictive analytics
Key Integrations
Designed to unify data across existing systems.
Strengths
A unified data view for organizations with many disconnected systems.
Considerations
Built primarily for hospitals and health systems, so groups should confirm scope and cost at their size.
Best For
Organizations with fragmented data wanting a unified RCM data layer.
6. Optum
Overview
Optum offers enterprise RCM technology and advisory services spanning ambulatory revenue cycle, claims and reimbursement, and patient access and payments.
Capabilities
- Ambulatory revenue cycle technology
- Middle revenue cycle through Optum Integrity One
- Real-time payer connectivity through Optum Real
- Patient access and payments
Key Integrations
Connects with a broad base of EHR and payer systems.
Strengths
National scale and a wide connectivity footprint.
Considerations
Sized for enterprise operations, so groups should confirm implementation effort and cost.
Best For
Enterprise organizations wanting RCM technology and advisory at national scale.
7. Epic Resolute
Overview
Epic Resolute is the revenue cycle suite inside the Epic EHR, covering Hospital Billing and Professional Billing.
Capabilities
- Hospital and professional billing
- Single Billing Office statements
- Benefits Engine for coverage checks
- Charge Router
Key Integrations
Native to Epic's clinical modules.
Strengths
No synchronization delay between clinical and billing data inside Epic.
Considerations
Built for Epic environments only.
Best For
Hospitals and medical groups standardized on Epic.
8. Oracle Health
Overview
Oracle Health offers an EHR-native revenue cycle suite for hospitals on its clinical platform.
Capabilities
- Patient administration and registration
- Case management and denial monitoring
- Health information management
- Patient accounting and payments
Key Integrations
Native to the Oracle Health EHR.
Strengths
Tight integration for hospitals on Oracle Health.
Considerations
Built for Oracle Health environments only.
Best For
Hospitals standardized on Oracle Health.
9. R1 RCM
Overview
R1 RCM is a tech-enabled outsourced revenue cycle provider built on its Phare platform.
Capabilities
- Front-end registration and eligibility
- Coding assistance and claim submission
- Payment posting and appeals
- Human review of complex cases
Key Integrations
Integrates with major EHRs as part of its outsourced model.
Strengths
End-to-end outsourcing for large health systems.
Considerations
An outsourced services relationship, so groups that want to keep revenue cycle work in-house should compare software options.
Best For
Large health systems wanting an outsourced revenue cycle.
10. Ensemble Health Partners
Overview
Ensemble Health Partners is a tech-enabled outsourced revenue cycle provider built on its EIQ platform.
Capabilities
- Claims data analytics
- AI-assisted appeal drafting with clinical oversight
- Conversational AI for payer and patient interactions
- Payment anomaly detection
Key Integrations
Integrates with existing EHR and billing systems as part of its outsourced model.
Strengths
A data-heavy managed services model.
Considerations
An outsourced partnership rather than software a group runs itself.
Best For
Health systems wanting a tech-enabled outsourced partnership.
Platform Comparison by Focus
The Work Between the Systems
Most RCM software is built around structured data: a claim, a code, a remittance. The revenue a group loses often sits in the conversations around that data. A payer representative confirms an authorization requirement that never reached the chart. A denial needs a call to find out what the payer actually wants. A patient will pay a balance once someone explains it.
Those conversations are where staff time goes and where revenue leaks when the team falls behind. Confido Health runs that work inside the systems a group already has, so claims engines get cleaner inputs and fewer balances age out. See our comparison of RCM and AI-driven operations for more.
Why CFOs and VPs of Revenue Cycle Choose Confido Health
Problems caught before the claim
Eligibility and authorization are confirmed while the patient books, so issues surface before a claim goes out.
Denials worked, not stacked
AI Teammates call payers, correct and resubmit claims, and track appeals, so fewer denials expire unworked.
Patient balances collected earlier
Balance explanations, payment plans, and collections calls run on a set cadence, so payments come in before balances age.
No rip-and-replace
Confido Health works inside the EHR, PMS, and billing systems a group already runs, with one standard at every location.
Final Thoughts
The right RCM strategy for a multi-location group depends on where revenue leaks. Waystar, Experian Health, Availity, and FinThrive cover claims, eligibility, and connectivity. Epic Resolute and Oracle Health fit organizations standardized on those EHRs. R1 RCM and Ensemble serve health systems that want to outsource. Optum brings national scale. Confido Health is built for groups that want the payer and patient work across the revenue cycle, from eligibility and authorization to denials and collections, handled end to end inside the systems they already run.
Before you choose, map where your revenue leaks by stage and location, and ask each vendor to show a pending authorization, a denial, and a patient balance moving to resolution in your own systems.
See Where Your Revenue Leaks
Running 10+ locations or providers? Send us your aging report and denial breakdown by location, and we will show you which balances and denials Confido Health would work first.
Book a demo or browse our specialty webinars.
Frequently Asked Questions
What is the best revenue cycle management software for multi-location groups?
For groups with 10+ providers, Confido Health is the strongest fit for the payer and patient work that decides collections: eligibility, authorization, denial follow-up and resubmission, and patient billing conversations, all inside the billing system the group already runs.
Does Confido Health handle denial management?
Yes. Confido Health AI Teammates classify denials by reason, call payers to confirm what is missing, correct and resubmit claims, and track appeals to resolution, with every update written back to the EHR or PMS.
Do we need to replace our billing system to use Confido Health?
No. Confido Health runs inside the EHR, PMS, and billing systems a group already uses, so groups add capacity without a migration.
How does Confido Health compare with Waystar?
Waystar focuses on claims, denials, and payment integrity. Confido Health handles the payer calls and patient billing conversations around those claims, so denials get worked and balances get collected without adding to staff workload.
How does Confido Health compare with Experian Health?
Experian Health provides front-end eligibility and authorization tools. Confido Health covers the same front end and continues through denial follow-up and patient collections, with AI Teammates making the payer and patient calls.
How does Confido Health compare with outsourcing to R1 RCM or Ensemble?
R1 RCM and Ensemble take over the revenue cycle as a service. Confido Health keeps the revenue cycle in-house and adds AI Teammates who run the payer and patient work, so the group keeps control and visibility.
Does Confido Health work with Epic Resolute or Oracle Health?
Yes. Confido Health integrates with Epic and other major EHRs and works alongside EHR-native billing, handling the payer and patient conversations those systems leave to staff.
What results have groups seen with Confido Health?
A 70-location ophthalmology group grew monthly collections to more than 3 times prior levels. See the Customer Results section above for details.
Is Confido Health HIPAA compliant?
Yes. Confido Health is HIPAA compliant, SOC 2 Type II certified, and signs a Business Associate Agreement with every customer.
